فراوانی دیابت تیپ 2 و عوامل مؤثر بر آن در بیماران مبتلا به سندرم تخمدان پلی کیستیک در درمانگاه‌های منتخب زنان دانشگاه علوم پزشکی شیراز 1383

Background & Aims: Polycystic ovarian syndrome is one of the most common hyper androgenic disorders in reproductive age. Women with lack of ovulation and hyper androgenic are exposed to non-insulin dependent diabetes. Our goal was the survey of abnormal glucose tolerance, insulin resistance and risk factors that affect the incidence of diabetes type2 in patients with polycystic ovary syndrome (PCOs).Materials & Methods: In this descriptive – analytic study 150 patients with simple purposive sampling method were selected. Among the subjects, laboratory tests were performed on 125 patients. Data collection tools were included Questionnaire, weight scale, measuring tape, fasting blood sugar test, fasting insulin and glucose tolerance test by75 gr glucose. Prevalence of diabetes type 2 and age relation, BMI, central obesity, glucose tolerance and insulin resistance measured and then data were analyzed using SPSS software and Chi square statistical tests. Results: Abnormal glucose tolerance rate was 8 percent. Also 14.4 percent of the patients had impaired fasting glucose and 4 percent of the patients had diabetes type 2 according to the results of the fasting blood sugar test.In8.9 percent of the subjects insulin resistance was observed. In 66 percent of the patients BMI was equal or more than 25 kg/m2. 76 percent of the patients had android obesity. Also a positive correlation between waist to hip ratio and glucose tolerance (r=0.25) and significant statistical difference was seen in these two parameters.Conclusion: Due to the emergence of insulin resistance and diabetes in patients with polycystic ovary syndrome, screening for IGT and diabetes type 2 in these patients is recommended.Source: Urmia Med J 2011: 22(1): 83 ISSN: 1027-3727